Chronic fatigue, fibromyalgia and energy production

Round & About

I regularly see clients with chronic fatigue syndrome (CFS) – fatigue so debilitating that they are virtually unable to function. Often CFS presents as fibromyalgia, which is chronic fatigue with the added burden of widespread pain and stiffness all over the body.

It is believed the pain associated with fibromyalgia is caused when the mitochondria (the energy production plants in our cells), desperate to supply energy to the body, switch from efficient aerobic (using oxygen) to inefficient anaerobic (no oxygen) metabolism. Anaerobic energy production creates large amounts of lactic acid.

Lactic acid, as anyone who pushes themselves when exercising knows, causes muscle pain, which dissipates after a short rest. This pain, however, does not dissipate with fibromyalgia, as the body is unable to break lactic acid down, due to mitochondrial dysfunction. The excess acid can also cause damage to muscle tissue, presenting as very sensitive areas. This process can feed on itself as the damage releases lots of free radicals (destructive molecules), which can cause additional damage if antioxidant status (the ability to neutralise free radical damage) is low. So mitochondrial dysfunction is one of the key areas when it comes to helping move the body back into balance with CFS and fibromyalgia. Healthy mitochondria require a raft of key nutrients for optimal performance, including but not limited to magnesium, B vitamins, essential fats, CoQ10, carnitine and alpha lipoic acid and must not be bathed in toxins. There are often multiple systemic imbalances going on, including but not limited to digestive dysfunction, poor antioxidant status, immune system dysregulation, chronic inflammation, viral infections, food and/or environmental sensitivities/allergies, thyroid and adrenal dysfunction and micronutrient deficiencies. Nothing exists in isolation. Once again looking at the body from a functional and holistic perspective is key.

Call Mark BSc (Hons) BA (Hons) mBANT CNHC on 01183 219533 or visit www.entirewellbeing.com

The gut and mental health

Round & About

It is not a new concept that a ‘gut brain’ axis exists and I have touched on this subject before in previous columns.

Serotonin is a neurotransmitter that regulates mood, appetite and sleep; when there are appropriate levels in the brain we feel relaxed and positive. This is the principle behind selective serotonin reuptake inhibitor drugs (SSRIs), to increase levels of serotonin available to the central nervous system. It is the gut, not the brain, however that is responsible for over 90% of total serotonin production.

In the gut, serotonin controls how ‘regular’ you are and it is the balance of the bacterial species in our gut that appears to play a significant role in the amount of serotonin produced. This might well explain not only why a significant relationship exists between individuals presenting with irritable bowel syndrome (IBS) and depression, but also why when doctors prescribe SSRIs for depression, those presenting with IBS often see improvements in digestive function.

A new study has found evidence in humans (not rodents as was the case until now) that our emotional responses, including anxiety and depression vary considerably depending on bacterial balance in the gut. The results not only suggest a strong link between the bacterial composition of our guts and feelings, but that the balance may change the physical structure of the brain by either growing the frontal cortex or shrinking the hippocampus – areas of the brain involved in problem solving, emotional regulation and consciousness. Understanding that gut microflora can play such a huge role in chemical balance of the brain is one thing, but that these microbes might initiate physical changes in the brain is another! This may well be why in clinical practice I often see clients’ overall mental health and wellbeing improve as we identify and eliminate key food and environmental sensitivities and support overall gut health.

Call Mark BSc (Hons) BA (Hons) mBANT CNHC on 01183 219533 or visit www.entirewellbeing.com